Distinct molecular subtype of prostate cancer identified
A collaborative expedition into the deep genetics of prostate cancer has uncovered a distinct subtype of the disease, one that appears to account for up to 15 percent of all cases, say researchers at...
View ArticleScientists unravel role of fusion gene in prostate cancer
Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes...
View ArticleGene mutation can allow proteins to gather, spark tumor growth
Prostate cancer is generally treated as if it's a single disease. But researchers have discovered a new type of the cancer that appears to affect 15 percent of patients, a finding that paves the way...
View ArticleNovel test streamlines testing for Huntington Disease
A new test may help to streamline genetic testing for Huntington Disease (HD) by generating accurate results, avoiding unnecessary additional testing, and improving turnaround time. The test, which...
View ArticleBone marrow cells migrate to tumors and can slow their growth
Bone marrow-derived cells (BMDCs) participate in the growth and spread of tumors of the breast, brain, lung, and stomach. To examine the role of BMDCs, researchers developed a mouse model that could be...
View ArticleAstrocytes: More than just glue
Epileptic fits are like thunderstorms raging in the brain: Nerve cells excite each other in an uncontrolled way so that strong, rhythmic electrical discharges sweep over whole brain regions. In the...
View ArticleStem cells improve visual function in blind mice
An experimental treatment for blindness, developed from a patient's skin cells, improved the vision of blind mice in a study conducted by Columbia ophthalmologists and stem cell researchers.
View ArticleAlzheimer's disease in mice alleviated promising therapeutic approach for humans
Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the...
View ArticlePromising drug slows down advance of Parkinson's disease and improves symptoms
Treating Parkinson's disease patients with the experimental drug GM1 ganglioside improved symptoms and slowed their progression during a two and a half-year trial, Thomas Jefferson University...
View ArticlePathological gambling caused by excessive optimism
Compulsive gamblers suffer from an optimism bias that modifies their subjective representation of probability and affects their decisions in situations involving high-risk monetary wagers. This is the...
View ArticleNew animal model gives insights into mechanisms of Parkinson's disease...
In Parkinson's disease, the protein "alpha-synuclein" aggregates and accumulates within neurons. Specific areas of the brain become progressively affected as the disease develops and advances. The...
View ArticleVeterinary researcher validates human tracheal/bronchial-cell model for...
A recently hired veterinary pathologist is bringing multiple skills to her new position in the College of Veterinary Medicine at Kansas State University, including experience with a human primary cell...
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